This exploratory analysis of a randomized clinical trial investigates the effect of KIT and PDGFRA mutations on recurrence-free survival in a population of patients with gastrointestinal stromal tumors treated with surgery and adjuvant imatinib.
This case-control cohort study compares the birth outcomes of adolescent and young adult cancer survivors with those of women without a cancer diagnosis.
This study compares the local tumor immune microenvironment in anal squamous cell carcinomas from HIV-positive and HIV-negative patients.
This review investigates recent advances in the understanding of the genetics of small cell carcinoma of the urinary bladder and the potential implications in diagnosis, prognosis, and treatment.
This Viewpoint examines the conclusions of the ProtecT randomized clinical trial and argues that, instead of radical therapy, appropriate patients for active surveillance should be chosen and active surveillance strategies optimized to avoid the small increased risk of distant metastasis seen in ProtecT.
This population-based cohort study uses the SEER database to characterize the incidence proportion of brain metastases at the time of cancer diagnosis among patients with breast cancer on a population-based level.
This review examines androgen receptor (AR)-related pathways, specific AR-targeted therapies, and the development of predictive biomarkers to stratify patients by likelihood of response to AR-targeted therapies.
This study compares the performance of 4 programmed cell death ligand 1 platforms, including 2 assays cleared by the US Food and Drug Administration and 2 laboratory-developed tests.
This study compares the overall survival of women diagnosed with breast cancer during pregnancy or in the postpartum period with that of women who had breast cancer but did not become pregnant.
This survey evaluates pediatric patients’ and parents’ perceptions of symptom burden during early cancer treatment and assesses their attitudes toward early integration of palliative care in pediatric oncology.
This updated analysis of a subset in the ASSURE clinical trial examines the disease-free survival and overall survival of high-risk patients with clear cell renal cancer treated with sunitinib, sorafenib, or placebo.
This randomized clinical trial compares 10-year survival rates for 2 adjuvant combination therapies for early breast cancer: docetaxel followed by cyclophosphamide, epirubicin, and fluorouracil vs docetaxel plus capecitabine followed cyclophosphamide, epirubicin, and capecitabine.
This meta-analysis establishes weighted effect sizes to compare exercise, psychological, combined exercise and psychological, and pharmaceutical interventions to treat cancer-related fatigue among patients with cancer during and after therapy.
This medical record review assesses the clinical and radiologic responses to cladribine for the treatment of adults with Erdheim-Chester disease.
A woman in her 30s presented with a palpable, nontender, firm mass in the neck. She had a medical history of high-grade osteosarcoma with areas of leimyosarcoma of the tibia. What is your diagnosis?